BostonGene and Sylvester Comprehensive Cancer Center at the University of Miami Collaborate to Advance Care for Cancer Patients
BostonGene, a leading provider of AI-driven molecular and immune profiling solutions, and Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, a research-focused medical school dedicated to discovering, developing and delivering lifesaving treatments, today announced a master agreement to propel collaborative research between the two organizations. Leveraging BostonGene's expertise in AI-powered molecular and immune profiling solutions and Sylvester’s extensive research capabilities, the collaboration will focus on validating blood- and bone marrow-based assays for hematological cancers.
"The collaboration between BostonGene and Sylvester Comprehensive Cancer Center holds immense promise for advancing cancer care, particularly for hematological cancer patients. By combining next-generation sequencing (NGS)-based tumor profiling with traditional diagnostic methods like fluorescence in situ hybridization (FISH) and cytogenetics, we aim to improve the accuracy of molecular subtyping, which is vital for personalized treatments," said C. Ola Landgren, M.D., Ph.D., director of Sylvester’s Myeloma Research Institute.
In the flagship study, researchers at Sylvester and BostonGene will evaluate the utility of bone marrow aspirates for clinical testing in multiple myeloma patients. Furthermore, traditional methodologies such as FISH and cytogenetics will be compared with BostonGene's NGS-based tumor profiling technique to identify molecular subtypes of multiple myeloma. Through this comparative analysis, the study will elucidate the strengths and limitations of each approach, ultimately contributing to the refinement of diagnostic and prognostic strategies in managing multiple myeloma.
"Through our collaboration with Sylvester, we're applying BostonGene's innovative AI and molecular profiling technologies to better understand and treat hematological cancers. Our goal is to fundamentally change how these cancers are diagnosed and managed, bringing us closer to a future where cancer care is precisely tailored to each patient's unique condition," said Nathan Fowler, M.D., Chief Medical Officer at BostonGene.
About BostonGene Corporation
BostonGene powers an AI model of tumor and immune biology to deliver disease-level insights and enable precision decision-making across oncology and immune-mediated diseases, spanning drug development and clinical care. By integrating multimodal data, including genomic, transcriptomic, immune, and clinical signals, BostonGene generates biologically grounded intelligence to optimize patient selection, trial design, and therapeutic strategy. This creates a scalable AI decision layer that improves development outcomes and clinical management. BostonGene partners with leading biopharmaceutical organizations and academic institutions to accelerate the delivery of precision therapies while continuously expanding its capabilities across new diseases and complex biological systems. For more information, visit www.BostonGene.com.About Sylvester Comprehensive Cancer Center
Sylvester Comprehensive Cancer Center, part of UHealth - University of Miami Health System and the University of Miami Miller School of Medicine, is the only National Cancer Institute (NCI) designated cancer center in South Florida. We are known as South Florida’s leader in patient-focused cancer research and care and offer the only phase 1 clinical trials in the region. Sylvester is a high performing cancer center among the nation’s top 10% in leukemia, lymphoma and myeloma, and in colon, lung, ovarian, prostate and uterine cancer surgeries. With a network of 10 facilities in South Florida and one office in Southwest Florida, Sylvester operates 15 site disease groups including transplant and cellular therapy and skin, thoracic, myeloma, lymphoma, gynecological, genitourinary, gastrointestinal, neuro-oncology, sarcoma, pediatric, endocrine, leukemia/hematology, breast and head and neck cancers. For more information, visit Sylvester.org and follow @Sylveste-Cancer on LinkedIn, Facebook, Twitter, Instagram and YouTube.
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