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Waltham, Mass • 2026-02-17

BostonGene Announces Strategic Collaboration with Daiichi Sankyo to Accelerate Drug Development Through AI-Driven Multimodal Analytics

AI Foundation Models to Enable Precision ADC Clinical Development and Response Intelligence

BostonGene, the developer of the leading AI foundation model for tumor and immune biology, today announced a strategic collaboration with Daiichi Sankyo (TSE: 4568). The collaboration will integrate AI-driven translational intelligence into the core of an antibody drug conjugate (ADC) development program of Daiichi Sankyo to move beyond standard exploratory biomarker analysis and deliver decision-ready insights that directly inform patient selection strategies, development prioritization and translational positioning.

"Success in modern drug development is no longer defined by data volume, but by the speed and accuracy with which we translate biological complexity into clinical outcomes,” said Nathan Fowler, MD, Chief Medical Officer at BostonGene. “Our work with Daiichi Sankyo is focused on accelerating learning cycles, lowering the cost of uncertainty, and differentiating this medicine earlier by identifying where it will most likely benefit patients with cancer.”

By generating digital twin representations from hundreds of thousands of multiomic and histopathologic patient profiles, BostonGene identifies the precise biological signatures and efficacy-associated mechanisms that distinguish responders from non-responders. This deep molecular mapping will enable the collaboration to define unique molecular subgroups by benchmarking the investigational medicine relative to approved treatments and existing standards of care. Additionally, these analyses will help enable clear asset differentiation by identifying unique therapeutic profiles and biological advantages. The platform also provides actionable insights into resistance pathways and the tumor microenvironment necessary to optimize future trial design and clinical positioning.

About BostonGene Corporation

BostonGene powers an AI model of tumor and immune biology to deliver disease-level insights and enable precision decision-making across oncology and immune-mediated diseases, spanning drug development and clinical care. By integrating multimodal data, including genomic, transcriptomic, immune, and clinical signals, BostonGene generates biologically grounded intelligence to optimize patient selection, trial design, and therapeutic strategy. This creates a scalable AI decision layer that improves development outcomes and clinical management. BostonGene partners with leading biopharmaceutical organizations and academic institutions to accelerate the delivery of precision therapies while continuously expanding its capabilities across new diseases and complex biological systems. For more information, visit www.BostonGene.com.

Erin Keleher

Senior Director

+1-617-283-2285

[email protected]