Liquid Biopsy

BostonGene’s blood-based Liquid Biopsy test provides comprehensive genomic profiling when tissue testing is not an option. For each patient, 216 genes, including 200 genes with complete exonic (coding) coverage, are evaluated to inform clinical decision-making.
All FDA and NCCN pan-cancer biomarkers from a routine blood sample
SNVs
SNVs and INDELs
216
Pan-cancer biomarkers
27
Fusions
TMB
Tumor mutational burden
CNAs
Copy number alterations
MSI
Microsatellite instability
Gene panel
Colorectal cancer
Breast cancer
Gastric cancer
Lung cancer
Melanoma
Ovarian cancer
Prostate cancer
Pancreatic cancer
Sarcoma
Thyroid cancer
AIP
AKT1
AKT2
ALK
APC
AR
ARAF
ARID1A
ARID1B
ATM
ATR
ATRX
AURKA
AXIN2
B2M
BAP1
BARD1
BLM
BMPR1A
BRAF
BRCA1
BRCA2
BRIP1
CASR
CCND1
CCND2
CCNE1
CD274
CD74
CDC73
CDH1
CDK12
CDK4
CDK6
CDKN1A
CDKN1B
CDKN1C
CDKN2A
CDKN2B
CHEK1
CHEK2
COL1A1
CTNNA1
CTNNB1
CYP17A1
DDR2
DICER1
DIS3L2
DPYD
EGFR
EIF1AX
EMSY
EPCAM
ERBB2
ERBB3
ERBB4
ERCC2
ERCC3
ERCC4
ERCC5
ERCC6
ERG
ESR1
ETV6
EWSR1
EZH2
EZR
FANCA
FANCB
FANCC
FANCD2
FANCE
FANCF
FANCG
FANCI
FANCL
FANCM
FBXW7
FGF19
FGFR1
FGFR2
FGFR3
FGFR4
FH
FLCN
FLI1
FLT3
FUS
GNA11
GNAQ
GNAS
GPC3
H3-3A
H3C2
HDAC1
HOXB13
HRAS
IDH1
IDH2
JAK2
KDM6A
KDR
KEAP1
KIT
KRAS
MAP2K1
MAP2K2
MAP3K1
MAPK1
MAPK3
MAX
MCPH1
MDM2
MDM4
MEN1
MET
MITF
MLH1
MLH3
MSH2
MSH3
MSH6
MTOR
MUTYH
MYC
MYCN
NBN
NF1
NF2
NFE2L2
NOTCH1
NOTCH2
NOTCH3
NOTCH4
NPM1
NRAS
NRG1
NTHL1
NTRK1
NTRK2
NTRK3
PALB2
PARP1
PBRM1
PDCD1LG2
PDGFB
PDGFRA
PDGFRB
PGR
PHOX2B
PIK3CA
PIK3CB
PIK3R1
PIK3R2
PMS1
PMS2
POLD1
POLE
POT1
PPP2R1A
PPP2R2A
PRCC
PRKAR1A
PTCH1
PTCH2
PTEN
PTPN11
RAD50
RAD51
RAD51B
RAD51C
RAD51D
RAD54L
RAF1
RB1
RECQL4
RET
RICTOR
RIT1
RNASEL
RNF43
ROS1
RSPO2
SDC4
SDHA
SDHAF2
SDHB
SDHC
SDHD
SETD2
SF3B1
SLC34A2
SLX4
SMAD4
SMARCA4
SMARCB1
SMARCE1
SMO
SPOP
STAG2
STK11
SUFU
TACC3
TERT
TFE3
TFEB
TMEM127
TMPRSS2
TP53
TSC1
TSC2
VEGFA
VHL
WRN
WT1
XRCC1
Enhanced analytics for accurate results
Fusion calling
Detection of 27 gene fusions and translocations
Error reduction algorithm
Optimal Liquid Biopsy sensitivity
White blood cell sequencing
CHIP filtration and incidental germline findings
Mobile phlebotomy
We offer professional in-home blood collection services.
Learn more about Liquid Biopsy