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Unknown Primary test

Determine the origin of tumors in patients with cancer of unknown primary or uncertain diagnosis using advanced DNA and RNA profiling. The Unknown Primary test can be seamlessly integrated into the BostonGene Tumor Portrait® order for a more precise diagnosis.

Resolving diagnostic uncertainty with advanced DNA and RNA profiling

The BostonGene Unknown Primary test utilizes AI-powered analysis of patients' molecular data to clarify challenging diagnoses and guide the selection of cancer-specific treatments.

The 32 most common solid tumors can be identified

Breast cancer
  • Basal-like breast cancer
  • Non-basal-like breast cancer
Melanoma
Renal cell carcinoma
  • Papillary renal cell carcinoma
  • Chromophobe renal cell carcinoma
  • Clear cell renal cell carcinoma
Gastrointestinal adenocarcinoma
  • Colorectal adenocarcinoma
  • Gastric or esophageal adenocarcinoma
Neuroendocrine tumor
Squamous cell carcinoma
  • Cervical squamous cell carcinoma
  • Squamous cell lung carcinoma
  • Squamous cell carcinoma of the head and neck or esophagus
Glioma
  • Astrocytoma
  • Glioblastoma
  • Oligodendroglioma
Ovarian cancer
Sarcoma
Germ cell neoplasm
Pheochromocytoma
Thymoma
Liver neoplasm
Thyroid neoplasm
Uterine corpus endometrial carcinoma
Lung adenocarcinoma
Pancreatic adenocarcinoma
Urinary bladder urothelial carcinoma
Prostate adenocarcinoma

Unknown Primary test: case example

Male, 81 y.o. at diagnosis. Poorly differentiated metastatic carcinoma with sarcomatoid elements 
View our publication

The powerful synergy of AI and pathologist expertise for tailored treatment plans

Each Unknown Primary report is independently validated by a certified pathologist to ensure precise tumor origin prediction. BostonGene also offers the option to update the Tumor Portrait report, incorporating cancer-specific findings and tailored treatment recommendations.

Two tests from one tissue sample

  • Tumor Portrait test - comprehensive genomic profiling
  • Unknown Primary test - tumor origin prediction
No extra tissue
Order add-on test via Tumor Portrait